What are you using this car for?
VQ sounds so awesome ON PAPER. But once you start actually comparing the costs of swapping one vs an LSx, you quickly see why VQ swaps aren't as popular. By the time you finish swapping a VQde into your S-Chassis, you could have probably just bought a HR 350z or maybe even a 370Z for about the same money.
Once you add that fact that VQde's are complete dogs when it comes to making more power, it really seems obvious to me.
But I do actually like the VQ in it's native chassis. It's a total workhouse, kinda like the KA.
If you are concerned about the weight distribution of an LSx with T56 in an S-Chassis...